Improvement of hand dexterity following motor cortex rTMS in multiple sclerosis patients with cerebellar impairment.
Koch, G ; Rossi, S ; Prosperetti, C ; et al. ; - ASI Sponsor
Aug - 2008
ISSN : 1352-4585 ;
journal : Multiple sclerosis (Houndmills, Basingstoke, England)

Issue : 7
type: Article Journal

Abstract
We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n=8) but not in healthy subjects (n=7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.

keywords : Adult,Cerebellar Ataxia,Cerebellar Ataxia: etiology,Cerebellar Ataxia: physiopathology,Cerebellar Ataxia: therapy,Cerebellum,Cerebellum: physiopathology,Female,Hand,Hand: physiology,Humans,Male,Middle Aged,Motor Cortex,Motor Cortex: physiology,Movement,Movement: physiology,Multiple Sclerosis,Relapsing-Remitting,Relapsing-Remitting: complicat,Relapsing-Remitting: physiopat,Relapsing-Remitting: therapy,Transcranial Magnetic Stimulation