Nanocomposite polymeric electrolytes to record electrophysiological brain signals in prolonged, unconventional or extreme conditions.
Licoccia, Silvia ; Luisa Di Vona, M ; Romagnoli, Paola ; et al. ; - ASI Sponsor
Sep - 2006
ISSN : 1742-7061 ;
journal : Acta biomaterialia

Issue : 5
type: Article Journal

Abstract
Chemically stable nanocomposite iono-conducting polymeric membranes (based on lithium salts and nanocrystalline oxide powders dispersed in a polymethyl methacrylate matrix) performed successfully in the recording of human brain responses to visual stimulation. Impedance was higher than that of conventional electrodes. However, the electrophysiological signals recorded by acid Al(2)O(3) and neutral Al(2)O(3) 5 wt.\% and 10 wt.\% nanocomposite gel electrolytes were comparable to those obtained with standard electrodes, even without preliminary skin cleaning and in the absence of gel electrolytes allowing better contact with and skin-electrode ionic conductance. The electrochemical and mechanical characteristics of these membranes make them fit for human and animal research, for clinical application (specifically in emergencies, prolonged electrophysiological recordings), or in unconventional or extreme conditions when fluid electrolytes are unsuitable (e.g., biomedical space research).

keywords : ALTEA,ASI - Sponsor,Animals,Biocompatible Materials,Brain,Brain: physiology,Electrodes,Electroencephalography,Electroencephalography: methods,Electrolytes,Electrophysiology,Evoked Potentials,Gels,Humans,Materials Testing,Nanotechnology,Polymers,Polymethyl Methacrylate,Visual